Sustanon 250 Cycle | Best Dosage For Bodybuilding – The Ultimate Guide

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Written By Jonathan Deventer

Produced by Organon, Sustanon 250 is a popular anabolic which contains a distinctive blend of four Testosterone esters, delivering a unique, staggered release of the hormone after injection. Our Sustanon 250 cycle guide takes a closer look at this renowned Testosterone blend, including popular cycles and stacks.

The first, crucial thing to understand about Sustanon 250 is it’s simply a Testosterone blend.

In the same way, Testosterone propionate and Testosterone enanthate both deliver the same identical anabolic hormone – Testosterone; the same is true for Sustanon 250. When you inject Sustanon 250 (often abbreviated to “Sust”) the anabolic hormone you are injecting is Testosterone.

It is therefore an excellent steroid for increasing muscle mass, strength and power.

Sustanon 250 cycle’s unique property when compared to the likes of Testosterone propionate or enanthate is the fact it is a blend of four different esters, as opposed to just one.

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“Ester”, what’s that and why does it matter?

As explained in our Testosterone guidean ester is a carbon chain attached to the Testosterone molecule which slows the release of the hormone in the body.

At one end of the spectrum is Testosterone with no esters attached, such as Testosterone suspension. Once injected, the hormone is quickly released in the body and causes a fairly rapid spike of Testosterone, which remains elevated for only a short period of time.

On the other end of the spectrum, we have the likes of Testosterone enanthate and cypionate which contain long ester chains, resulting in a slower release of Testosterone after injection and subsequently an elevated level of the hormone lasting a couple of weeks.

In-between the two we have the various other esters. The propionate ester is a popular choice for Testosterone users who want a fairly quick elevation of the steroid which lasts only several days.

For bodybuilders and athletes, the important thing to note is the need to keep a relatively stable concentration of the hormone in the system to produce the desired anabolic-androgenic benefits, yet avoid the undesirable side effects caused by chaotic hormone levels. For this reason, shorter esters require regular injections (daily or every other day), whereas longer esters such as enanthate typically only require injections once or twice a week.

This is where Sustanon 250 cycle is unique. It contains both quick releasing propionate and phenylpropionate esters, and slower releasing decanoate and isocaproate esters – resulting in a blend that effectively produces a quick, yet enduring release of Testosterone. Like Testosterone enanthate, Sustanon 250 can be injected once or twice per week, yet users will notice the quicker Testosterone release brought about by the propionate and phenylpropionate esters in the blend.

It is always advisable to go with the original Organon product (which is pharmaceutical grade) and avoid underground versions which try to mimic the Sustanon blend. Sustanon 250 cycle is usually fairly easy and inexpensive to source.

Each ampule contains 250mg of Testosterone, composed as follows; 100mg of Testosterone decanoate, 60mg of Testosterone Isocaproate, 60mg of Testosterone phenylpropionate and 30mg of Testosterone propionate.

Sustanon 250 Cycle Results To Expect


Being the primary, naturally occurring male hormone, Testosterone is numero-uno in the world of anabolic-androgenic steroids. It is generally well-tolerated and is widely considered the best choice for someone’s first cycle, as well as providing the perfect base compound for experienced bodybuilders when stacking several hormones together.

While results vary from person to person and depend on a whole host of other variables, we can reasonably expect Testosterone to cause significant increases in muscle size and strength. Those who are fairly new to anabolics and aim to gain muscle mass typically report Sustanon 250 cycles producing 10-20lbs of weight gain over the course of a cycle and about half of it is kept once the cycle is ceased and water retention normalises.

For those who have already tried other Testosterone esters, there should in theory be little difference between them and Sustanon 250. This is something to keep in mind for those who have discovered they are prone to side effects from previous Testosterone cycles, as Sustanon 250 cycle is likely to prove no different.

Sustanon 250 Cycles With Dosage And Stacks

Bulking Cycle

Testosterone is a versatile hormonesuitable for both bulking and cutting cycles alike, and it makes a perfect base when stacking with other anabolics.

Like Testosterone enanthate, Sustanon 250 cycle is typically used during the bulking cycle where maximum muscle gain is the goal. Great results can be achieved from running Sustanon on its own, yet many choose to stack it with other steroids which are also suited for adding mass, such as Dianabol.

Sustanon 250 cycle is also effective, either on its own or stacked with other compounds, for cutting cycles. The goal for most athletes and bodybuilders during a cutting cycle is body fat reduction whilst retaining as much muscle mass as possible in the catabolic environment brought about by dieting. A moderate dose of Sustanon 250 will successfully preserve lean tissue during a cut and is often stacked with other compounds which aid fat loss and muscle hardening. Additionally, when using Sustanon 250 cycle for cutting, the use of an anti-aromatase in low doses can prove particularly useful for preventing water retention.

For informational purposes, here are some ideas for Sustanon 250 cycles and stacks:

Sustanon 250 Cycle For Beginners

 Sustanon 250
Week 1500mg (per week)
Week 2500mg (per week)
Week 3500mg (per week)
Week 4500mg (per week)
Week 5500mg (per week)
Week 6500mg (per week)
Week 7500mg (per week)
Week 8500mg (per week)
Week 9500mg (per week)
Week 10500mg (per week)
Week 11500mg (per week)
Week 12500mg (per week)
Week 13 
Week 14 
Week 15 
Week 16PCT
Week 17PCT
Week 18PCT

Sustanon 250 Cycle With Deca Durabolin And Dianabol

 Sustanon 250Deca DurabolinDianabol
Week 1500mg (per week)400mg (per week)40mg (per day)
Week 2500mg (per week)400mg (per week)40mg (per day)
Week 3500mg (per week)400mg (per week)40mg (per day)
Week 4500mg (per week)400mg (per week)40mg (per day)
Week 5500mg (per week)400mg (per week)40mg (per day)
Week 6500mg (per week)400mg (per week)40mg (per day)
Week 7500mg (per week)400mg (per week) 
Week 8500mg (per week)400mg (per week) 
Week 9500mg (per week)400mg (per week) 
Week 10500mg (per week)400mg (per week) 
Week 11500mg (per week)400mg (per week) 
Week 12500mg (per week)400mg (per week) 
Week 13 
Week 14 
Week 15 
Week 16PCT
Week 17PCT
Week 18PCT

Sustanon 250 Cycle For Cutting (with Anastrozole to prevent water retention)

 Sustanon 250Anastrozole
Week 1350mg (per week*)0.5mg (each other day)
Week 2350mg (per week)0.5mg (each other day)
Week 3350mg (per week)0.5mg (each other day)
Week 4350mg (per week)0.5mg (each other day)
Week 5350mg (per week)0.5mg (each other day)
Week 6350mg (per week)0.5mg (each other day)
Week 7350mg (per week)0.5mg (each other day)
Week 8350mg (per week)0.5mg (each other day)
Week 9350mg (per week)0.5mg (each other day)
Week 10350mg (per week)0.5mg (each other day)
Week 11350mg (per week)0.5mg (each other day)
Week 12350mg (per week)0.5mg (each other day)
Week 13 
Week 14 
Week 15 
Week 16PCT
Week 17PCT
Week 18PCT

* Equal to pinning 250mg every 5 days

Sustanon 250 Cycle With Trenbolone

 Sustanon 250Trenbolone
Week 1500mg (per week)500mg (per week)
Week 2500mg (per week)500mg (per week)
Week 3500mg (per week)500mg (per week)
Week 4500mg (per week)500mg (per week)
Week 5500mg (per week)500mg (per week)
Week 6500mg (per week)500mg (per week)
Week 7500mg (per week)500mg (per week)
Week 8500mg (per week)500mg (per week)
Week 9500mg (per week)500mg (per week)
Week 10500mg (per week)500mg (per week)
Week 11500mg (per week)500mg (per week)
Week 12500mg (per week)500mg (per week)
Week 13 
Week 14 
Week 15 
Week 16PCT
Week 17PCT
Week 18PCT
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Sustanon 250 Side Effects

As with the other Testosterone products, Sustanon 250 cycle can produce several undesirable side effects.

Firstly, androgenic related side effects including oily skin, acne, accelerated baldness and increased aggressiveness are fairly common. Like all hormones, tolerance differs from person to person and it’s usually only possible to properly gauge sensitivity once a cycle is embarked upon. That said, if you are particularly prone to acne breakouts or currently suffer from male pattern baldness, Testosterone and other androgenic steroids can be expected to worsen such conditions.

Another potential source of unwanted side effects is the heightened oestrogen levels that can build up during a Sustanon 250 cycle due to the aromatization of testosterone into oestrogens. Heightened oestrogen levels can cause increased water retention and Gynecomastia – the formation of breast tissue.

The initial stages of Gynecomastia typically involve itchy or sore nipples, developing into a notable mass of tissue behind (or close to behind) the nipple. If left unchecked the tissue can continue to build and is only rectifiable with surgery.

Thankfully most people find Testosterone tolerable and do not suffer from the likes of Gynecomastia. For those that do, the oestrogen related side effects can usually be controlled with either an anti-oestrogen or anti-aromatase.

Anti-oestrogen products (such as Nolvadex and Clomid) actively compete with oestrogen at the oestrogen receptors, reducing oestrogenic effects. Both Nolvadex and Clomid are inexpensive and easy to source – it’s always advisable to have an ample supply on hand during and after a cycle. They are also the primary drugs used during Post Cycle Therapy (PCT).

While anti-oestrogens may negate the effects of increased oestrogen, it is possible to actually reduce the level of the hormone in the body by taking an anti-aromatase drug, such as Proviron or Anastrozole. These drugs reduce the conversion of testosterone into oestrogen in the first place and are typically taken during a cycle by those who are prone to oestrogenic side effects.

At the end of any cycle always ensure you run a proper Post Cycle Therapy to help restore your natural hormone production which will have been suppressed.

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