Oxandrolone Tablets – How they Work and Safety Review

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Written By Jonathan Deventer

Oxandrolone Tablets, also known as Anavar tablets or capsules, are among over a dozen anabolic-androgenic steroids popular with bodybuilders and athletes wishing to not only increase their athletic capabilities but their physique.

Anabolic-androgenic steroids are most often associated with bodybuilders and athletes who use them to rapidly increase muscle growth and power, but medically supervised, are also used in the treatment of numerous medical conditions.

Also Read: Oxandrolone Genesis Labs 10 mg Tablets

Before taking any drug, and most especially illegally purchased Oxandrolone tablets or other forms of anabolic steroids, know how they work, what to expect in regard to results, and most importantly, safety considerations for use. Click here to visit our recommended supplier.

How do Oxandrolone Tablets work?


It’s always important to know what a specific drug is supposed to do in the body whether you’re taking it on doctor’s orders or not.

The same applies to Oxandrolone tablets.

Oxandrolone tablets have a similar mechanism of action as other anabolic steroids, mainly serving as an androgen receptor agonist.

Oxandrolone triggers the activity of androgen (sex characteristic) hormones in targeting specific receptor cells.

Such links or connections require Cell A to find and zone in on Cell B to initiate a function or activity.

Think of it like interlocking pieces of a puzzle. Or round pegs sliding into round holes and square pegs into square holes. A round peg won’t fit into a square hole and vice versa.

This cellular receptor activity demands that these cells “connect” to a specific target in order to trigger specific actions.

Androgen receptors are considered a type of protein. The main function of steroid hormone receptors has to do with cellular proliferation and differentiation.

The proliferation defines the growth of new cells. In regard to bodybuilding, this focus is on new muscle cell growth.


This growth has been studied in medical and scientific research, especially when applied to its uses in critical care scenarios, for burn victims, and the potential growth of infants diagnosed with complex congenital heart disease.

Oxandrolone (Anavar) is clinically indicated and may be recommended in some countries like the UK to promote weight gain.

This is often required by patients dealing with chronic illness, a complicated or very long surgical procedure, or individuals who simply can’t gain or maintain a normal weight.

Oxandrolone also reduces catabolism (damage or destruction) of proteins, most specifically in scenarios involving the long-term use of corticosteroids.

Oxandrolone Tablets Dosage

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Dosage recommendations for any drug, including Oxandrolone tablets, will depend on numerous factors. In medical scenarios, these factors mainly revolve around a condition being treated.

When taken for nonmedical reasons such as used by bodybuilders and athletes, dosage recommendations for Oxandrolone tablets vary depending on the bodybuilding websites, discussion groups, and forum board reviews.

The half-life of Oxandrolone is approximately 9 to 10 hours depending on milligram strength.

Oxandrolone is produced in a variety of tablet milligram strengths: 2.5 mg and 10 mg (also applies to Oxandrin, another brand of Oxandrolone).

For therapeutic use, Oxandrolone tablets (most commonly the 2.5 mg) were recommended in an overall daily dosage that ranges from 2.5 mg to 20 mg a day, although somewhere in the middle was most common.

The drug is recommended in cycles that last two to four weeks.

In nonmedical scenarios (as used by bodybuilders), dosage averages 15 mg to 25 mg a day for between six and eight weeks.

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Bodybuilders often combine anabolic steroids with testosterone for greater impact and results, as well as other drugs designed to minimize the potential for side effects when it comes to progestational or estrogenic side effects.

This process of stacking or combining drugs, regardless of what they are or what they’re supposed to do, can contribute to an increased risk of side effects and adverse reactions.

Safety considerations when using oxandrolone tablets

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Oxandrolone, available in oral tablet form has the potential to interfere with otherwise normal lipid (fat) balances in the body, more specifically cholesterol concentration levels.

Oxandrolone tablets, like other anabolic steroids, may decrease levels of good or HDL high-density lipoprotein cholesterol, which is required for good heart health.

It may also increase levels of bad or LDL low-density lipoprotein cholesterol, which contributes to atherosclerosis, which in turn increases the risk of clogged arteries, heart attack, and stroke.

Even at low doses, Oxandrolone tablets may affect liver function.

Individuals diagnosed or predisposed to conditions such as cancer, heart conditions, kidney problems, or any type of liver dysfunction should avoid use.

Oxandrolone tablets are contraindicated in the presence of prostate cancer conditions or male or female breast cancer, and hypercalcemia.

Women who are pregnant or planning to become pregnant or breastfeeding should avoid anabolic steroids and other drugs, even low-dose Oxandrolone tablets.

Oxandrolone tablets may encourage muscle growth that provides rather impressive results for many users, but take the time to research the potential for dependence, side effects, and adverse reactions.

In many cases, the use of anabolic-androgenic steroids benefits doesn’t outweigh the risks of use.

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  6. Grunfeld C. Oxandrolone in the treatment of HIV-associated weight loss in men: a randomized, double-blind, placebo-controlled study. J Acquir Immune Defic Syndr. 2006 Mar.
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