However, Clenbuterol is a stimulant, or sympathomimetic amine, and not an anabolic steroid. Other drugs in this family are Adderall, Ephedrine, Albuterol, and Caffeine. This is a large category of drugs, and the above drugs, plus Clenbuterol, Norepinephrine, Epinephrine, etc. are similar to each other and can be thought of as cousins or siblings.
Clenbuterol, specifically, uses a few different methods to stimulate the sympathomimetic central nervous system. It accomplishes this through adrenoreceptors, which are contained within many different tissues in the body. Click here to buy Clen online.
Throughout the tissues which contain these receptors, Clen will create different effects when it meets the receptor, according to the type of cells that contain the receptors.
There are about nine different types of adrenoreceptors in the human body. Because of this, they are labeled by number and as either Alpha or Beta. For instance, the body contains receptors known as Beta-1, Beta-2, Beta-3, etc., and the same for Alpha.
The various sympathomimetic and stimulant compounds are different from their siblings and cousins not only in what actions they do but in how they act upon these various receptors.
Clen in particular is known for how it interacts with Beta-2 receptors. This explains why it is known as a Beta-2 receptor agonist.
How this relates to the fat-burning effects of Clenbuterol will be discussed more extensively. We will also explain more about how the mechanism of action differs from steroids, but point out that there are some anabolic properties of Clen which is why it may be stacked together with other anabolic steroids in a bodybuilding cycle.
However, the primary effects of this stimulant relate to increasing metabolic activity to burn fat as opposed to building muscle.
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Is Clenbuterol a Steroid
Despite the fact that Clenbuterol is used mainly to burn fat among those in entertainment and athletic circles, it was first used in medicine for something quite different.
Sympathomimetics and stimulants of all kinds are used in medicine for treating many different medical problems, and most medical conditions that they are used for can be treated with a variety of medications in this class.
Clenbuterol has been used for the treatment of asthma. It is a primary ingredient in many asthma inhalers, though it isn’t used in the US any longer for this purpose, with Albuterol taking its place.
Clenbuterol is very effective in the treatment of asthma since it activates Beta-2 receptors, particularly those in cells located in the lining of the bronchial tubes. This causes bronchial dilation in the throat, nose, and lungs so that the airways are expanded.
All sympathomimetics have some degree of usage for bronchial dilation. The human body creates its own neurotransmitters (Norepinephrine and Epinephrine, also known as Noradrenaline and Adrenaline), that also work as sympathomimetic stimulants, but to a much greater degree.
Clenbuterol is also used medically to treat anaphylactic shock, histamine reactions, swelling and allergic reactions, migraine headaches, arrhythmias, cardiovascular slowdown or shock, and hypertension.
As mentioned earlier, Clenbuterol works as a Beta-2 agonist since it does work primarily on the body’s Beta-2 receptors, but it does work with additional receptor sites as well, just not to as significant of a degree, and with less significant results.
For instance, if you compare Ephedrine and Clenbuterol, you will see that while Ephedrine works on a great deal of both Alpha and Beta receptors equally, Clenbuterol mainly affects Beta-2 receptors.
To put it in simple terms, if the receptors were a collection of nails sticking out of a piece of wood, the effect of Clenbuterol is similar to using a small hammer to nail one nail individually, in comparison to Ephedrine, which is like hitting all the nails at once with a sledgehammer.
This example isn’t perfect, but it is a good summary of the way Clenbuterol works. Check out the best Cutting Stacks with Clenbuterol.
Does Clenbuterol have Anabolic Effects like Steroids?
We have talked about how Clenbuterol is used in medicine, for bronchodilation, as well as its other medical uses. We have yet to talk about and explain the main use of Clenbuterol in weight loss: the effect it has on the metabolism of fat.
Clenbuterol is known for its minor anabolic function in muscle tissues, with animal research demonstrating a clear anabolic effect on muscle tissue. However, it is a minor and very mild effect.
These studies have shown, that bodybuilders, as well as other human users, have shown that the anabolic effects of Clenbuterol are minor if they are even seen at all.
Research looking at the effect of Clenbuterol on rat skeletal muscle tissue showed that it does have a small anabolic effect on animals, however, it must be used for an extended period of time to have these effects.
This means that anyone looking to use Clenbuterol for an anabolic reason will probably be disappointed. Clenbuterol, when taken with steroids for performance or physique enhancement, must be seen above all as an aid to help you lose fat, and not for anabolic uses since it is not effective for this.
Also, it is important to note that these slight anabolic effects in animals were seen after giving them doses that would be very dangerous and extreme in humans. Because of this, many hypothesize that Clenbuterol may not have any anabolic effect on humans at all.
Clen Promotes Fat Loss while Sparing Muscle
Despite this, the selective action of Clenbuterol on Beta-2 receptors gives Clen its ability to significantly boost fat loss. By activating Beta-2 receptors that are in the fat cell membranes, it can activate and begin the metabolism of fat cells directly, beginning the triglyceride breakdown process, in which they are converted into free fatty acids.
The Beta-2 receptors located on fat cells directly influence the metabolism of fat, maybe more than the other Alpha and Beta receptors the fat cells possess. This increase in the metabolism of fat is why Clenbuterol has often been given to cattle in the past, along with a variety of anabolic steroids, so that the cattle would have more lean meat.
It is also important to keep in mind that Clenbuterol may work differently in different individuals. Some people may lose more fat with Clenbuterol, while some might find that they lose more fat with drugs such as Ephedrine since it reacts with a wider variety of receptors than does Clenbuterol.
However, the important thing to note is that though Clenbuterol works well to stimulate fat loss for most people, there are those non-responders, those who don’t respond well, who do exist. The half-life of Clenbuterol is about 36 to 48 hours, so there is no need to take more than one dose throughout the day, just once daily is enough. Click here to shop for Clenbuterol Pills.
Clenbuterol and Tolerance/Downregulation
The last thing to point out concerning the agonistic activity of Clenbuterol is that it downregulates Beta-2 receptors. When you use Clenbuterol daily, Beta-2 receptors will regulate, or get used to the activity of Clenbuterol.
This means that Clen’s effect on fat loss will diminish over time. This can be dealt with through a couple of different methods. The first is to take two weeks or more off of Clen.
Research has shown, however, that using the anti-histamine Ketotifen Fumarate will up-regulate the Beta-2 receptors that Clen down-regulates. We will talk about this more later, but in about the second or third week of using Clenbuterol, fat loss begins to diminish, though the time frame is different for each person.
This is why it is typically used in bodybuilding cutting cycles for a short period of time. Then, you may decide to cycle off and use other anabolic steroids to help you bulk up and build muscle. But do not expect to build a lot of muscle during the time that you are taking Clen.